Study wrapper · #995
Kisspeptin-10 regulates glycosaminoglycan and decorin content in human cardiac fibroblast cultures.
Radwańska P, Olkiewicz M, Piera L, et al. Pharmacological reports. 2026.
DOI: 10.1007/s43440-026-00870-6PubMed: 42159865
Editor's note
A cell-culture study, not a human or animal trial, so findings speak only to mechanism. Kisspeptin-10 was the direct subject and showed a dose-dependent, receptor-dependent signal associated with cardiac extracellular-matrix remodeling that would need in vivo confirmation.
Plain-language abstract
In cultured human heart fibroblast cells, kisspeptin-10 increased production of extracellular-matrix components through GPR54 and FAK signaling.
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