Study wrapper · #982
Dynamic modulation of LH secretion by continuous kisspeptin infusion in healthy men.
Naveed A, Lippincott MF, Stamou M, et al. Hormones (Athens, Greece). 2026.
DOI: 10.1007/s42000-026-00795-yPubMed: 42236284b
Editor's note
This is a direct human study administering kisspeptin-10 by continuous infusion and tracking reproductive hormone responses. The sample is only three men and the design is exploratory physiology, so it is a preliminary signal rather than a controlled trial. Genuinely on-topic for how kisspeptin acts in humans, including the partial desensitization observed over 24 hours.
Plain-language abstract
In three healthy men, a continuous 24-hour infusion of kisspeptin-10 rapidly raised LH several-fold, after which levels partly declined, with modest parallel rises in FSH and testosterone. This was a small human physiology study.
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