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Study wrapper · #1292

Tirzepatide as a possible trigger of bullous pemphigoid: A case report.

Hernández Madrid P, Gotor Rivera A, Alejo Fernández-Baillo JL, et al. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2026.
Weak / noneCase reportMentions: Tirzepatide

Editor's note

A single case report in JDDG, the weakest design for linking a drug to an adverse event: it can raise a question but cannot speak to how often this happens or whether the drug caused it. Bullous pemphigoid has an established association with other diabetes agents, notably DPP-4 inhibitors, which makes an incretin-era report worth logging. Without full text, the timing, any rechallenge and other exposures are unknown, so readers should regard it strictly as a hypothesis.

Plain-language abstract

Clinicians describe a patient who developed bullous pemphigoid, a blistering skin condition, after starting tirzepatide. The authors regard the drug as a possible trigger. This is a single case, and the record carries no abstract with the supporting detail.