Latest studies

Peptide Therapies in Thyroid Health: Emerging Applications in Endocrine and Immune Modulation.

This narrative review in Integrative Medicine surveys the mechanistic rationale and existing evidence for several peptides — thymosin alpha-1, thymosin beta-4, BPC-157, and growth hormone secretagogues — as potential adjuncts in thyroid disorders, particularly Hashimoto's thyroiditis. The authors' own framing is appropriately cautious: the evidence base consists primarily of preclinical investigations, mechanistic studies, and early exploratory clinical reports, not thyroid-focused randomised controlled trials. As a narrative review, this study synthesises existing literature rather than generating new data — which means its conclusions are shaped by what research already exists, including its gaps. Narrative reviews are also susceptible to selection bias in ways that systematic reviews with predefined search protocols are not. The peptide context reinforces the authors' restraint. Thymosin alpha-1 carries the strongest human evidence base of the group, but that evidence covers hepatitis and oncology indications — not thyroid disease. BPC-157 remains almost entirely preclinical. The thyroid-specific evidence gap the review identifies is real and significant. Readers should...