Study wrapper · #990
Mitochondrial-targeted SS-31 peptide attenuates radiation-induced cardiomyocyte senescence.
Xie L, Wu J, Fan J, et al. Journal of radiation research. 2026.
DOI: 10.1093/jrr/rrag048PubMed: 42456009
Editor's note
A cell-culture study in which SS-31 was the direct intervention and showed a consistent signal against radiation-induced senescence markers. Findings are mechanistic and preclinical, not evidence of clinical benefit in people.
Plain-language abstract
In cultured rat and human heart-muscle cells, the mitochondria-targeted peptide SS-31 reduced markers of radiation-induced cellular aging and oxidative stress.
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