Study wrapper · #986
Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness and Mucus Hypersecretion.
Xie M, Weng J, Li C, et al. Lung. 2026.
DOI: 10.1007/s00408-026-00875-1PubMed: 41801306
Editor's note
An animal and cell study directly comparing SS-31 and N-acetylcysteine in ozone-induced airway injury, with SS-31 as a primary intervention. Findings are preclinical and mechanistic, not evidence of human benefit.
Plain-language abstract
In a mouse model of ozone-induced airway injury, SS-31 reduced airway reactivity, inflammation, and mucus, comparably to N-acetylcysteine.
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