Study wrapper · #877
GLP-1 Receptor Agonists and Fertility: What Is Known So Far?
Editor's note
A narrative review of GLP-1 receptor agonists in fertility and PCOS care, where most of the reproductive-outcome evidence comes from liraglutide and exenatide rather than the peptides we track. Semaglutide and tirzepatide appear mainly around safety and washout guidance, and narrative reviews carry selection risk. The pregnancy-contraindication and washout points are the most durable takeaways for our readers.
Plain-language abstract
This narrative review summarizes evidence that GLP-1 receptor agonists may improve reproductive outcomes in women with PCOS and obesity-related infertility, mostly from liraglutide and exenatide data. It stresses that semaglutide and tirzepatide are contraindicated in pregnancy and require a washout period before conception.